multi drug resistant strains escherichia coli atcc baa 2471  (ATCC)

Journal: Scientific Reports

Article Title: Synthesis and biological evaluation of novel aminoguanidine derivatives as potential antibacterial agents

doi: 10.1038/s41598-024-77668-0

Figure Lengend Snippet: MIC a (µg/mL) of small molecules 4a-f , 5a-i and 9a-c against drug-sensitive bacteria.

Article Snippet: The strains of multidrug-resistant clinical isolates were multi-drug resistant Staphylococcus aureus ATCC 43,300 and multi-drug resistant Escherichia coli ATCC BAA-196.

Techniques: Bacteria

Journal: Scientific Reports

Article Title: Synthesis and biological evaluation of novel aminoguanidine derivatives as potential antibacterial agents

doi: 10.1038/s41598-024-77668-0

Figure Lengend Snippet: Antibacterial activity and cytotoxicity for 5f .

Article Snippet: The strains of multidrug-resistant clinical isolates were multi-drug resistant Staphylococcus aureus ATCC 43,300 and multi-drug resistant Escherichia coli ATCC BAA-196.

Techniques: Activity Assay

Journal: Scientific Reports

Article Title: Synthesis and biological evaluation of novel aminoguanidine derivatives as potential antibacterial agents

doi: 10.1038/s41598-024-77668-0

Figure Lengend Snippet: ( A ) DIZ of S.aureus treated by Gatifoxacin, 5f and 1% DMSO respectively; ( B ) DIZ of E. coli treated by Gatifoxacin, 5f and 1% DMSO respectively.

Article Snippet: The strains of multidrug-resistant clinical isolates were multi-drug resistant Staphylococcus aureus ATCC 43,300 and multi-drug resistant Escherichia coli ATCC BAA-196.

Techniques:

Journal: Scientific Reports

Article Title: Synthesis and biological evaluation of novel aminoguanidine derivatives as potential antibacterial agents

doi: 10.1038/s41598-024-77668-0

Figure Lengend Snippet: Transmission electron micrographs of ( A ) untreated E. coli ATCC 25,922; ( B ) treated with 5f . The arrows mark areas of membrane damage and cell content release. Scale bar 500 nm.

Article Snippet: The strains of multidrug-resistant clinical isolates were multi-drug resistant Staphylococcus aureus ATCC 43,300 and multi-drug resistant Escherichia coli ATCC BAA-196.

Techniques: Transmission Assay, Membrane

Journal: Scientific Reports

Article Title: Synthesis and biological evaluation of novel aminoguanidine derivatives as potential antibacterial agents

doi: 10.1038/s41598-024-77668-0

Figure Lengend Snippet: MIC a (µg/mL) of small molecules 4a-f , 5a-i and 9a-c against drug-sensitive bacteria.

Article Snippet: In this trial, compound 5f had excellent inhibitory activity against the multi-drug resistant E. coli ATCC BAA-196 and S. aureus ATCC 43,300, with a MIC of 4 and 8 μg/mL, respectively (Table ).

Techniques: Bacteria

Journal: Scientific Reports

Article Title: Synthesis and biological evaluation of novel aminoguanidine derivatives as potential antibacterial agents

doi: 10.1038/s41598-024-77668-0

Figure Lengend Snippet: Antibacterial activity and cytotoxicity for 5f .

Article Snippet: In this trial, compound 5f had excellent inhibitory activity against the multi-drug resistant E. coli ATCC BAA-196 and S. aureus ATCC 43,300, with a MIC of 4 and 8 μg/mL, respectively (Table ).

Techniques: Activity Assay

Journal: Scientific Reports

Article Title: Synthesis and biological evaluation of novel aminoguanidine derivatives as potential antibacterial agents

doi: 10.1038/s41598-024-77668-0

Figure Lengend Snippet: ( A ) DIZ of S.aureus treated by Gatifoxacin, 5f and 1% DMSO respectively; ( B ) DIZ of E. coli treated by Gatifoxacin, 5f and 1% DMSO respectively.

Article Snippet: In this trial, compound 5f had excellent inhibitory activity against the multi-drug resistant E. coli ATCC BAA-196 and S. aureus ATCC 43,300, with a MIC of 4 and 8 μg/mL, respectively (Table ).

Techniques:

Journal: Scientific Reports

Article Title: Synthesis and biological evaluation of novel aminoguanidine derivatives as potential antibacterial agents

doi: 10.1038/s41598-024-77668-0

Figure Lengend Snippet: Transmission electron micrographs of ( A ) untreated E. coli ATCC 25,922; ( B ) treated with 5f . The arrows mark areas of membrane damage and cell content release. Scale bar 500 nm.

Article Snippet: In this trial, compound 5f had excellent inhibitory activity against the multi-drug resistant E. coli ATCC BAA-196 and S. aureus ATCC 43,300, with a MIC of 4 and 8 μg/mL, respectively (Table ).

Techniques: Transmission Assay, Membrane